Peter Gibbons

Generation of quinolone antimalarials targeting the <i>Plasmodium falciparum</i> mitochondrial respiratory chain for the treatment and prophylaxis of malaria

Giancarlo A. Biagini, Nicholas Fisher, Alison E. Shone et al. · Proceedings of the National Academy of Sciences · 2012 · 156 citations

Evidence for a Common Non‐Heme Chelatable‐Iron‐Dependent Activation Mechanism for Semisynthetic and Synthetic Endoperoxide Antimalarial Drugs

Paul A. Stocks, Patrick G. Bray, Victoria Barton et al. · Angewandte Chemie International Edition · 2007 · 130 citations · Full text

Biochemistry, Antiparasitic Agent, Iron Metabolism +15

Identification, Design and Biological Evaluation of Bisaryl Quinolones Targeting <i>Plasmodium falciparum</i> Type II NADH:Quinone Oxidoreductase (PfNDH2)

Chandrakala Pidathala, Richard K. Amewu, Bénédicte Pacorel et al. · Journal of Medicinal Chemistry · 2012 · 109 citations · Full text

Drug Target, Plasmodium Falciparum, Biochemistry +14

Candidate Selection and Preclinical Evaluation of <i>N</i> - <i>tert</i> -Butyl Isoquine (GSK369796), An Affordable and Effective 4-Aminoquinoline Antimalarial for the 21st Century

Paul M. O’Neill, B. Kevin Park, Alison E. Shone et al. · Journal of Medicinal Chemistry · 2009 · 83 citations · Full text

Two-Step Synthesis of Achiral Dispiro-1,2,4,5-tetraoxanes with Outstanding Antimalarial Activity, Low Toxicity, and High-Stability Profiles

Gemma L. Ellis, Richard K. Amewu, Sunil Sabbani et al. · Journal of Medicinal Chemistry · 2008 · 82 citations

Bioorganic Chemistry, Antiparasitic Agent, Immunology +17