Shengqiang Shen

Novel Glycosylated Naphthalimide-Based Activatable Fluorescent Probe: A Tool for the Assessment of Hexosaminidase Activity and Intracellular Hexosaminidase Imaging

Lili Dong, Shengqiang Shen, Huizhe Lu et al. · ACS Sensors · 2019 · 29 citations

Life Sciences, Biochemistry, Molecular Biology +17

Synthesis, Optimization, and Evaluation of Glycosylated Naphthalimide Derivatives as Efficient and Selective Insect β-<i>N</i>-Acetylhexosaminidase OfHex1 Inhibitors

Shengqiang Shen, Lili Dong, Wei Chen et al. · Journal of Agricultural and Food Chemistry · 2019 · 26 citations

Pharmacy, Molecular Biology, Pharmacology +16

Discovery of Novel Inhibitors Targeting Human O-GlcNAcase: Docking-Based Virtual Screening, Biological Evaluation, Structural Modification, and Molecular Dynamics Simulation

Lili Dong, Shengqiang Shen, Wei Chen et al. · Journal of Chemical Information and Modeling · 2019 · 23 citations

Pharmacy, Medicinal Chemistry, Pharmacology +10

Modification of the Thioglycosyl–Naphthalimides as Potent and Selective Human O-GlcNAcase Inhibitors

Shengqiang Shen, Lili Dong, Wei Chen et al. · ACS Medicinal Chemistry Letters · 2018 · 16 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16