M. Håkansson

Protein Flexibility and Conformational Entropy in Ligand Design Targeting the Carbohydrate Recognition Domain of Galectin-3

Carl Diehl, Olof Engström, Tamara Delaine et al. · Journal of the American Chemical Society · 2010 · 231 citations · Full text

Life Sciences, Biochemistry, Biophysics +17

The Carbohydrate-Binding Site in Galectin-3 Is Preorganized To Recognize a Sugarlike Framework of Oxygens: Ultra-High-Resolution Structures and Water Dynamics

K. Saraboji, M. Håkansson, Samuel Genheden et al. · Biochemistry · 2011 · 162 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Crystal structures of the <i>Chromobacterium violaceum</i>ω‐transaminase reveal major structural rearrangements upon binding of coenzyme PLP

Maria Svedendahl Humble, Karim Engelmark Cassimjee, M. Håkansson et al. · FEBS Journal · 2012 · 123 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Monosaccharide Derivatives with Low‐Nanomolar Lectin Affinity and High Selectivity Based on Combined Fluorine–Amide, Phenyl–Arginine, Sulfur–π, and Halogen Bond Interactions

Fredrik R. Zetterberg, Kristoffer Peterson, Richard Johnsson et al. · ChemMedChem · 2017 · 106 citations

Pharmacy, Chemistry, Medicinal Chemistry +17

Systematic Tuning of Fluoro-galectin-3 Interactions Provides Thiodigalactoside Derivatives with Single-Digit nM Affinity and High Selectivity

Kristoffer Peterson, Rohit Kumar, Olof Stenström et al. · Journal of Medicinal Chemistry · 2017 · 99 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +16