Karen E. Parrish

Efflux Transporters at the Blood-Brain Barrier Limit Delivery and Efficacy of Cyclin-Dependent Kinase 4/6 Inhibitor Palbociclib (PD-0332991) in an Orthotopic Brain Tumor Model

Karen E. Parrish, Jenny L. Pokorny, Rajendar K. Mittapalli et al. · Journal of Pharmacology and Experimental Therapeutics · 2015 · 96 citations · Full text

Efficacy of PARP Inhibitor Rucaparib in Orthotopic Glioblastoma Xenografts Is Limited by Ineffective Drug Penetration into the Central Nervous System

Karen E. Parrish, Ling Cen, J. C. Murray et al. · Molecular Cancer Therapeutics · 2015 · 86 citations · Full text

Pharmacotherapy, High-grade Gliomas, Glioma +18

Enhanced antitumor immunity by a novel small molecule HPK1 inhibitor

Dan You, Stephen Hillerman, Gregory Locke et al. · Journal for ImmunoTherapy of Cancer · 2021 · 75 citations · Full text

Restricted Delivery of Talazoparib Across the Blood–Brain Barrier Limits the Sensitizing Effects of PARP Inhibition on Temozolomide Therapy in Glioblastoma

Sani H. Kizilbash, Shiv K. Gupta, Kenneth Tou En Chang et al. · Molecular Cancer Therapeutics · 2017 · 71 citations · Full text

ABCG2 and ABCB1 Limit the Efficacy of Dasatinib in a PDGF-B–Driven Brainstem Glioma Model

Rajendar K. Mittapalli, Karen E. Parrish, Donna Crabtree et al. · Molecular Cancer Therapeutics · 2016 · 59 citations · Full text

Chemoprevention Strategy, High-grade Gliomas, Dasatinib Delivery +21