Gabriella Pásztor

Cariprazine (RGH-188), a potent D3/D2 dopamine receptor partial agonist, binds to dopamine D3 receptors in vivo and shows antipsychotic-like and procognitive effects in rodents

István Gyertyán, Béla Kiss, Katalin Sághy et al. · Neurochemistry International · 2011 · 147 citations

Medicine, Pharmacology, Psychiatry +13

Occupancy of dopamine D2 and D3 and serotonin 5-HT1A receptors by the novel antipsychotic drug candidate, cariprazine (RGH-188), in monkey brain measured using positron emission tomography

Nicholas Seneca, Sjoerd J. Finnema, I. Laszlovszky et al. · Psychopharmacology · 2011 · 55 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Subnanomolar dopamine D3 receptor antagonism coupled to moderate D2 affinity results in favourable antipsychotic-like activity in rodent models: II. behavioural characterisation of RG-15

István Gyertyán, Katalin Sághy, Judit Laszy et al. · Naunyn-Schmiedeberg s Archives of Pharmacology · 2008 · 55 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Effects of RGH-237 [N-{4-[4-(3-Aminocarbonyl-phenyl)-piperazin-1-yl]-butyl}-4-bromo-benzamide], an Orally Active, Selective Dopamine D3 Receptor Partial Agonist in Animal Models of Cocaine Abuse

István Gyertyán, Béla Kiss, Krisztina Gál et al. · Journal of Pharmacology and Experimental Therapeutics · 2006 · 33 citations

Medicine, Medicinal Chemistry, Pharmacology +17