Ugo Zanelli

Procognitive and Neuroprotective Activity of a Novel α7 Nicotinic Acetylcholine Receptor Agonist for Treatment of Neurodegenerative and Cognitive Disorders

Renza Roncarati, Carla Scali, Thomas A. Comery et al. · Journal of Pharmacology and Experimental Therapeutics · 2009 · 99 citations

Medicine, Neuroscience, Pharmacology +17

Comparison of Cryopreserved HepaRG Cells with Cryopreserved Human Hepatocytes for Prediction of Clearance for 26 Drugs

Ugo Zanelli, Nicola P. Caradonna, David Hallifax et al. · Drug Metabolism and Disposition · 2011 · 74 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

M3258 Is a Selective Inhibitor of the Immunoproteasome Subunit LMP7 (β5i) Delivering Efficacy in Multiple Myeloma Models

Michael P. Sanderson, Manja Friese‐Hamim, Gina Walter-Bausch et al. · Molecular Cancer Therapeutics · 2021 · 37 citations · Full text

Medicine, Oncology, Pharmacology +14

Comparison of methods for the prediction of human clearance from hepatocyte intrinsic clearance for a set of reference compounds and an external evaluation set

Tetsuo Yamagata, Ugo Zanelli, Dieter Gallemann et al. · Xenobiotica · 2016 · 36 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Structure-Based Optimization and Discovery of M3258, a Specific Inhibitor of the Immunoproteasome Subunit LMP7 (β5i)

Markus Klein, Michael Busch, Manja Friese‐Hamim et al. · Journal of Medicinal Chemistry · 2021 · 36 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13