Guylène Le Meur

Restoration of vision in RPE65-deficient Briard dogs using an AAV serotype 4 vector that specifically targets the retinal pigmented epithelium

Guylène Le Meur, Knut Stieger, Alexander J. Smith et al. · Gene Therapy · 2006 · 200 citations

Biology, Rpe65-deficient Briard Dogs, Ocular Disease +10

Whole-Exome Sequencing Identifies Mutations in GPR179 Leading to Autosomal-Recessive Complete Congenital Stationary Night Blindness

Isabelle Audo, Kinga M. Bujakowska, Elise Orhan et al. · The American Journal of Human Genetics · 2012 · 132 citations · Full text

Ocular Disease, Developmental Biology, Mendelian Disorder +6

Safety and Long-Term Efficacy of AAV4 Gene Therapy in Patients with RPE65 Leber Congenital Amaurosis

Guylène Le Meur, Pierre Lebranchu, Fanny Billaud et al. · Molecular Therapy · 2017 · 126 citations · Full text

Long-term doxycycline-regulated transgene expression in the retina of nonhuman primates following subretinal injection of recombinant AAV vectors

Knut Stieger, Guylène Le Meur, Françoise Lasne et al. · Molecular Therapy · 2006 · 107 citations · Full text

Ganglion Cell, Ocular Disease, Signal Transduction +15

Biodistribution of rAAV Vectors Following Intraocular Administration: Evidence for the Presence and Persistence of Vector DNA in the Optic Nerve and in the Brain

Nathalie Provost, Guylène Le Meur, Michel Weber et al. · Molecular Therapy · 2004 · 87 citations · Full text