Jaime Kapitulnik

Tumorigenicity studies with diol-epoxides of benzo(a)pyrene which indicate that (+/-)-trans-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene is an ultimate carcinogen in newborn mice.

Jaime Kapitulnik, Peter G. Wislocki, Wayne Levin et al. · PubMed · 1978 · 240 citations

Medicine, Oncology, Carcinogenesis +13

Benzo[a]pyrene 7,8-dihydrodiol is more carcinogenic than benzo[a]pyrene in newborn mice

Jaime Kapitulnik, Wayne Levin, Allan H. Conney et al. · Nature · 1977 · 208 citations

Medicine, Toxicology, Carcinogenesis +10

Comparative metabolism of benzo[a]pyrene and drugs in human liver

Jaime Kapitulnik, P. J. Poppers, Allan H. Conney · Clinical Pharmacology & Therapeutics · 1977 · 104 citations

Medicine, Biochemistry, Pharmacology +13

Immunohistochemical localization of cytochrome P-450 in rat brain

Jaime Kapitulnik, H V Gelboin, F. Peter Guengerich et al. · Neuroscience · 1987 · 86 citations

Medicine, Neurobiology, Neuroscience +8

Marked endogenous activation of the CYP1A1 and CYP1A2 genes in the congenitally jaundiced Gunn rat.

Jaime Kapitulnik, Frank J. Gonzalez · Molecular Pharmacology · 1993 · 83 citations

Life Sciences, Biochemistry, Genetics +17