Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

Wesley C. Van Voorhis, John H. Adams, Roberto Adelfio, +182

PLoS Pathogens

Drug TargetBioorganic ChemistryAntiparasitic AgentMalariaMedicinal Chemistry +15

The Bactofilin Cytoskeleton Protein BacM of Myxococcus xanthus Forms an Extended β-Sheet Structure Likely Mediated by Hydrophobic Interactions

David M. Zuckerman, Lauren Boucher, Kefang Xie, +3

PLoS ONE

Filament FormationProtein AssemblyNm FilamentsProtein FoldingNatural Sciences +11

Polymorphic expression of a human superficial bladder tumor antigen defined by mouse monoclonal antibodies.

Yves Fradet, Najmul Islam, Lauren Boucher, +2

Proceedings of the National Academy of Sciences

HistocompatibilityUrologyImmunocytochemical TechniqueTumoral PathologyGenitourinary Cancer +11

DXP Synthase‐Catalyzed CN Bond Formation: Nitroso Substrate Specificity Studies Guide Selective Inhibitor Design

Francine Morris, Ryan J. Vierling, Lauren Boucher, +2

ChemBioChem

Identification of Biochemically Distinct Properties of the Small Ubiquitin-related Modifier (SUMO) Conjugation Pathway in Plasmodium falciparum

Katherine H. Reiter, Debaditya Mukhopadhyay, Hong Zhang, +4

Journal of Biological Chemistry

Reductive StressConjugation PathwaySmall Ubiquitin-related ModifiersProtein FunctionPlasmodium Falciparum +12

“Stapling” scFv for multispecific biotherapeutics of superior properties

Lauren Boucher, Elisabeth Geyer Prinslow, Michael Feldkamp, +27

mAbs

NanotherapeuticsScfv BreathingImmunologyMolecular BiologyPeptide Science +18

Characterization of 7A5: A Human CD137 (4-1BB) Receptor Binding Monoclonal Antibody with Differential Agonist Properties That Promotes Antitumor Immunity

Helen Kotanides, Rose Marie Sattler, Maria B. Lebron, +22

Molecular Cancer Therapeutics

Molecular assessment of intratumoral immune cell subsets and potential mechanisms of resistance to odronextamab, a CD20×CD3 bispecific antibody, in patients with relapsed/refractory B-cell non-Hodgkin lymphoma

Jurriaan Brouwer‐Visser, Nathalie Fiaschi, Raquel P. Deering, +16

Journal for ImmunoTherapy of Cancer

Structure of<i>Chlamydomonas reinhardtii</i>THB1, a group 1 truncated hemoglobin with a rare histidine–lysine heme ligation

Selena L. Rice, Lauren Boucher, J.L. Schlessman, +3

Acta Crystallographica Section F Structural Biology Communications

Nitrate AssimilationBiochemistryGroup 1Protein FoldingNitric Oxide +12

Characterization and Structural Insights into Selective E1-E2 Interactions in the Human and Plasmodium falciparum SUMO Conjugation Systems

Katherine H. Reiter, Anita Ramachandran, Xue Xia, +3

Journal of Biological Chemistry