Isabella Pearsall

Clonal fitness inferred from time-series modelling of single-cell cancer genomes

Sohrab Salehi, Farhia Kabeer, Nicholas Ceglia et al. · Nature · 2021 · 165 citations · Full text

Clonal Fitness, Functional Genomics, Tumor Heterogeneity +12

FOXC2 promotes vasculogenic mimicry and resistance to anti-angiogenic therapy

Ian G. Cannell, Kirsty Sawicka, Isabella Pearsall et al. · Cell Reports · 2023 · 47 citations · Full text

Angiogenesis, Immunology, Endothelial Dysfunction +10

Addiction of lung cancer cells to GOF p53 is promoted by up-regulation of epidermal growth factor receptor through multiple contacts with p53 transactivation domain and promoter

Catherine A. Vaughan, Isabella Pearsall, Shilpa Singh et al. · Oncotarget · 2016 · 38 citations · Full text

Allele specific gain-of-function activity of p53 mutants in lung cancer cells

Catherine A. Vaughan, Rebecca A. Frum, Isabella Pearsall et al. · Biochemical and Biophysical Research Communications · 2012 · 27 citations · Full text

Medicine, Tumor Suppressor, Cancer Genetics +8