Philip C. Sharpe

Dipyridyl Thiosemicarbazone Chelators with Potent and Selective Antitumor Activity Form Iron Complexes with Redox Activity

Des R. Richardson, Philip C. Sharpe, David B. Lovejoy et al. · Journal of Medicinal Chemistry · 2006 · 381 citations

Medicine, Medicinal Chemistry, Pharmacology +11

Novel Thiosemicarbazones of the ApT and DpT Series and Their Copper Complexes: Identification of Pronounced Redox Activity and Characterization of Their Antitumor Activity

Patric J. Jansson, Philip C. Sharpe, Paul V. Bernhardt et al. · Journal of Medicinal Chemistry · 2010 · 241 citations

Natural Sciences, Chemistry, Medicinal Chemistry +15

Design, Synthesis, and Characterization of Novel Iron Chelators:  Structure−Activity Relationships of the 2-Benzoylpyridine Thiosemicarbazone Series and Their 3-Nitrobenzoyl Analogues as Potent Antitumor Agents

Danuta S. Kalinowski, Yu Yu, Philip C. Sharpe et al. · Journal of Medicinal Chemistry · 2007 · 221 citations

Pharmacy, Chemistry, Medicinal Chemistry +14

Novel Second-Generation Di-2-Pyridylketone Thiosemicarbazones Show Synergism with Standard Chemotherapeutics and Demonstrate Potent Activity against Lung Cancer Xenografts after Oral and Intravenous Administration in Vivo

David B. Lovejoy, Danae M. Sharp, Nicole A. Seebacher et al. · Journal of Medicinal Chemistry · 2012 · 199 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

2-Acetylpyridine Thiosemicarbazones are Potent Iron Chelators and Antiproliferative Agents: Redox Activity, Iron Complexation and Characterization of their Antitumor Activity

Des R. Richardson, Danuta S. Kalinowski, Věra Richardson et al. · Journal of Medicinal Chemistry · 2009 · 199 citations

Pharmacy, Chemistry, Medicinal Chemistry +14