Mark Klein

CD4+CD25bright Regulatory T Cells Actively Regulate Inflammation in the Joints of Patients with the Remitting Form of Juvenile Idiopathic Arthritis

Ismé M. de Kleer, Lucy R. Wedderburn, Leonie S. Taams et al. · The Journal of Immunology · 2004 · 398 citations

Life Sciences, Cell Biology, Immunology +16

Autologous stem cell transplantation for autoimmunity induces immunologic self-tolerance by reprogramming autoreactive T cells and restoring the CD4+CD25+ immune regulatory network

Ismé de Kleer, Mark Klein, Gijs Teklenburg et al. · Blood · 2005 · 235 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells

Ellen J. Wehrens, Gerdien Mijnheer, Chantal L. Duurland et al. · Blood · 2011 · 163 citations

Life Sciences, Immunology, Pathology +17

Metastin (KiSS-1) Mimetics Identified from Peptide Structure−Activity Relationship-Derived Pharmacophores and Directed Small Molecule Database Screening

Michael J. Orsini, Mark Klein, Mary Pat Beavers et al. · Journal of Medicinal Chemistry · 2007 · 77 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Fcγ receptor antigen targeting potentiates cross-presentation by human blood and lymphoid tissue BDCA-3+ dendritic cells

T.W.H. Flinsenberg, Ewoud B. Compeer, Dan Koning et al. · Blood · 2012 · 73 citations · Full text

Life Sciences, Cell Biology, Immunology +13