Ellen J. Wehrens

High-resolution 3D imaging of fixed and cleared organoids

Johanna F. Dekkers, María Alieva, Lianne M. Wellens et al. · Nature Protocols · 2019 · 535 citations

Tissue Imaging, Radiology, Engineering +11

Early transcriptional and epigenetic regulation of CD8+ T cell differentiation revealed by single-cell RNA sequencing

Boyko Kakaradov, Janilyn Arsenio, Christella E. Widjaja et al. · Nature Immunology · 2017 · 246 citations

Chromatin, Transcriptional Regulation, Systems Biology +15

Long-term culture, genetic manipulation and xenotransplantation of human normal and breast cancer organoids

Johanna F. Dekkers, Esmée J. van Vliet, Norman Sachs et al. · Nature Protocols · 2021 · 240 citations · Full text

Breast Cancer Organoids, Long-term Culture, Xenotransplantation +11

Uncovering the mode of action of engineered T cells in patient cancer organoids

Johanna F. Dekkers, María Alieva, Astrid Cleven et al. · Nature Biotechnology · 2022 · 194 citations · Full text

Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells

Ellen J. Wehrens, Gerdien Mijnheer, Chantal L. Duurland et al. · Blood · 2011 · 162 citations