K Donaldson

Ultrafine particles and nitrogen oxides generated by gas and electric cooking

Martine Dennekamp, S Howarth, Colin A. J. Dick et al. · Occupational and Environmental Medicine · 2001 · 325 citations · Full text

Public Health, Food Science, Air Pollution +16

Cigarette Smoke Alters Chromatin Remodeling and Induces Proinflammatory Genes in Rat Lungs

John A. Marwick, Paul Kirkham, Christopher S. Stevenson et al. · American Journal of Respiratory Cell and Molecular Biology · 2004 · 301 citations

Life Sciences, Molecular Biology, Toxicology +9

Oxidant-mediated lung epithelial cell tolerance: the role of intracellular glutathione and nuclear factor-kappaB 1 1Abbreviations: A549 cells, human alveolar epithelial type II cell line; AP-1, activator protein-1; BSO; dl-buthionine (SR)-sulfoximine; COPD, chronic obstructive pulmonary disease; DMEM, Dulbecco’s modified Eagle’s medium; DTT, dithiothreitol; GSHMEE, glutathione monoethyl ester; H2O2, hydrogen peroxide; IkB, inhibitory binding protein kB; LDH, lactic dehydrogenase; NAC, N-acetyl-l-cysteine; NF-kB, nuclear factor-kappa b; NPSH, non-protein sulphydryls; PKC, protein kinase C; and ROS, reactive oxygen species.

Irfan Rahman, Brigitte Mulier, Peter S. Gilmour et al. · Biochemical Pharmacology · 2001 · 130 citations

Life Sciences, Cell Biology, Pharmacology +17

Molecular Mechanism of Transforming Growth Factor (TGF)-β1-induced Glutathione Depletion in Alveolar Epithelial Cells

Hazel Jardine, William MacNee, K Donaldson et al. · Journal of Biological Chemistry · 2002 · 105 citations · Full text

Life Sciences, Biochemistry, Cell Biology +17

Degradation of connective tissue components by lung derived leucocytes in vitro: role of proteases and oxidants.

Gillian Brown, K Donaldson · Thorax · 1988 · 39 citations · Full text

Life Sciences, Immunology, Pathology +17