An engineered PET depolymerase to break down and recycle plastic bottles

Vincent Tournier, Christopher M. Topham, A. Gilles, +17

Nature

Polymer UpcyclingChemical EngineeringPlastic BottlesEngineeringPlastic Recycling +11

An engineered enzyme embedded into PLA to make self-biodegradable plastic

Marie Guicherd, Maher Ben Khaled, Marc Guéroult, +17

Nature

BioplasticsEngineeringDegradable PlasticBioplasticBiochemical Engineering +8

The Src Homology 3 Domain Is Required for Junctional Adhesion Molecule Binding to the Third PDZ Domain of the Scaffolding Protein ZO-1

J. Nomme, Alan S. Fanning, Michael Caffrey, +3

Journal of Biological Chemistry

Structures of Apo and Product-Bound Human <scp>l</scp>-Asparaginase: Insights into the Mechanism of Autoproteolysis and Substrate Hydrolysis

J. Nomme, Ying Su, Manfred Konrad, +1

Biochemistry

Substrate HydrolysisBiosynthesisCellular EnzymologyBiochemistryAmino Acid +11

Structural Basis of a Key Factor Regulating the Affinity between the Zonula Occludens First PDZ Domain and Claudins

J. Nomme, Aleksandar Antanasijevic, Michael Caffrey, +4

Journal of Biological Chemistry

Design of Potent Inhibitors of Human RAD51 Recombinase Based on BRC Motifs of BRCA2 Protein: Modeling and Experimental Validation of a Chimera Peptide

J. Nomme, Axelle Renodon‐Cornière, Yuya Asanomi, +6

Journal of Medicinal Chemistry

Inhibition of filament formation of human Rad51 protein by a small peptide derived from the BRC‐motif of the BRCA2 protein

J. Nomme, Yoshimasa Takizawa, Susan F. Martinez, +6

Genes to Cells

Co-targeting of convergent nucleotide biosynthetic pathways for leukemia eradication

David A. Nathanson, Amanda L. Armijo, Michelle Tom, +24

The Journal of Experimental Medicine

Dctp BiosynthesisMedicineDctp ProductionCancer Cell BiologyLeukemia Eradication +9

Elucidation of the Specific Function of the Conserved Threonine Triad Responsible for Human l-Asparaginase Autocleavage and Substrate Hydrolysis

J. Nomme, Ying Su, Arnon Lavie

Journal of Molecular Biology

Substrate HydrolysisCellular EnzymologyBiochemistryNatural SciencesMolecular Biology +5

Free Glycine Accelerates the Autoproteolytic Activation of Human Asparaginase

Ying Su, Christos S. Karamitros, J. Nomme, +3

Chemistry & Biology

Protein SecretionBiochemistryNatural SciencesFree GlycineCellular Biochemistry +3