Christopher M. Topham

An engineered PET depolymerase to break down and recycle plastic bottles

Vincent Tournier, Christopher M. Topham, A. Gilles et al. · Nature · 2020 · 2.1K citations

Engineering, Materials Engineering, Materials Science +14

Prediction of the stability of protein mutants based on structural environment-dependent amino acid substitution and propensity tables

Christopher M. Topham, Narayanaswamy Srinivasan, T. L. Blundell · Protein Engineering Design and Selection · 1997 · 213 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Fragment Ranking in Modelling of Protein Structure

Christopher M. Topham, Alasdair McLeod, Frank Eisenmenger et al. · Journal of Molecular Biology · 1993 · 112 citations

Life Sciences, Biochemistry, Bioinformatics +7

Exploration of subsite binding specificity of human cathepsin D through kinetics and rule‐based molecular modeling

Paula E. Scarborough, Ben M. Dunn, Kunchur Guruprasad et al. · Protein Science · 1993 · 100 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Comparative modelling of major house dust mite allergen <i>Der p</i> I: structure validation using an extended environmental amino acid propensity table

Christopher M. Topham, N. Srinivasan, Christopher J. Thorpe et al. · Protein Engineering Design and Selection · 1994 · 88 citations

Life Sciences, Biochemistry, Bioinformatics +17