A Mutation in the Dimerization Domain of Filamin C Causes a Novel Type of Autosomal Dominant Myofibrillar Myopathy

Matthias Vorgerd, Peter F. M. van der Ven, Vera Bruchertseifer, +8

The American Journal of Human Genetics

Mendelian DisorderNovel TypeGeneticsMolecular BiologyMolecular Genetics +4

Indications for a Novel Muscular Dystrophy Pathway

Peter F. M. van der Ven, Sebastian Wiesner, Paula Salmikangas, +9

The Journal of Cell Biology

Skeletal Muscle CellsMolecular BiologyCytoskeletonCellular PhysiologyFilamin Domain +16

KIF5B and KIF3A/KIF3B kinesins drive MT1-MMP surface exposure, CD44 shedding, and extracellular matrix degradation in primary macrophages

Christiane Wiesner, Jan Faix, Mirko Himmel, +2

Blood

Xin repeats define a novel actin-binding motif

Dirk Pacholsky, Padmanabhan Vakeel, Mirko Himmel, +5

Journal of Cell Science

Skeletal Muscle CellsCardiac MuscleMolecular BiologyCytoskeletonCellular Physiology +15

Muscle-type Creatine Kinase Interacts with Central Domains of the M-band Proteins Myomesin and M-protein

Thorsten Hornemann, Stefan Kempa, Mirko Himmel, +3

Journal of Molecular Biology

M-band Proteins MyomesinProtein FunctionMolecular PhysiologySignal TransductionMuscle Function +11

Structural Determinants of Integrin Binding to the Talin Rod

Alexandre R. Gingras, Wolfgang Ziegler, Andrey A. Bobkov, +15

Journal of Biological Chemistry

Dimerisation of Myomesin: Implications for the Structure of the Sarcomeric M-band

Stephan Lange, Mirko Himmel, Daniel Auerbach, +4

Journal of Molecular Biology

Crystal StructureSarcomeric M-bandMolecular BiologyStructural BiologyMedicine +2

The Limits of Promiscuity:  Isoform-Specific Dimerization of Filamins

Mirko Himmel, Peter F. M. van der Ven, Walter Stöcklein, +1

Biochemistry

Protein SecretionMolecular BiologyCytoskeletonIsoform-specific DimerizationProtein Folding +16

Proteomic analysis of podosome fractions from macrophages reveals similarities to spreading initiation centres

Pasquale Cervero, Mirko Himmel, Marcus Krüger, +1

European Journal of Cell Biology

MedicineNatural SciencesCell TraffickingEndocytic PathwayCytoskeleton +10

The kinesin KIF9 and reggie/flotillin proteins regulate matrix degradation by macrophage podosomes

Susanne Cornfine, Mirko Himmel, Petra Kopp, +5

Molecular Biology of the Cell

Molecular BiologyCytoskeletonCellular PhysiologyMacrophage PodosomesCell Interaction +19