Marc R. de Jonge

Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 Variants

Kalyan Das, Arthur D. Clark, Paul Lewi et al. · Journal of Medicinal Chemistry · 2004 · 511 citations

Life Sciences, Medicinal Chemistry, Pharmacology +17

SYNOPSIS:  SYNthesize and OPtimize System in Silico

H. Maarten Vinkers, Marc R. de Jonge, Frederik F. D. Daeyaert et al. · Journal of Medicinal Chemistry · 2003 · 229 citations · Full text

Pharmacy, Medicinal Chemistry, Computational Chemistry +15

Evolution of anti-HIV drug candidates. Part 3: diarylpyrimidine (DAPY) analogues

Donald Ludovici, Bart L. De Corte, Michael J. Kukla et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 185 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Evolution of Anti-HIV Drug CandidatesPart 2: Diaryltriazine (DATA) Analogues

Donald Ludovici, Robert W. Kavash, Michael J. Kukla et al. · Bioorganic & Medicinal Chemistry Letters · 2001 · 126 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

A computational model of the inhibition of <i>Mycobacterium tuberculosis</i> ATPase by a new drug candidate R207910

Marc R. de Jonge, Luc Koymans, Jérôme Guillemont et al. · Proteins Structure Function and Bioinformatics · 2007 · 123 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17