Shi‐You Jiang

Discovery of a potent HMG-CoA reductase degrader that eliminates statin-induced reductase accumulation and lowers cholesterol

Shi‐You Jiang, Hui Li, Jingjie Tang et al. · Nature Communications · 2018 · 188 citations · Full text

Life Sciences, Biochemistry, Pharmacology +16

A <i>LIMA1</i> variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption

Yingyu Zhang, Zhen-Yan Fu, Jian Wei et al. · Science · 2018 · 162 citations

Life Sciences, Cardiology, Genetics +17

Discovery of an insulin‐induced gene binding compound that ameliorates nonalcoholic steatohepatitis by inhibiting sterol regulatory element‐binding protein–mediated lipogenesis

Shi‐You Jiang, Xinglin Yang, Zimo Yang et al. · Hepatology · 2022 · 57 citations

Life Sciences, Endocrinology, Pharmacology +17

Henryin, an ent-kaurane Diterpenoid, Inhibits Wnt Signaling through Interference with β-Catenin/TCF4 Interaction in Colorectal Cancer Cells

Xingyao Li, Jian‐Xin Pu, Shi‐You Jiang et al. · PLoS ONE · 2013 · 44 citations · Full text

Medicine, Oncology, Pharmacology +16

Discovery of Natural Potent HMG‐CoA Reductase Degraders for Lowering Cholesterol

Xiao‐Zheng Su, Linfei Zhang, Kun Hu et al. · Angewandte Chemie International Edition · 2023 · 27 citations

Life Sciences, Botany, Plant Sciences +15