Tsuyoshi Karibe

A Novel HER3-Targeting Antibody–Drug Conjugate, U3-1402, Exhibits Potent Therapeutic Efficacy through the Delivery of Cytotoxic Payload by Efficient Internalization

Yuuri Hashimoto, Kumiko Koyama, Yasuki Kamai et al. · Clinical Cancer Research · 2019 · 174 citations

Medicine, Oncology, Pharmacology +15

Prediction of Human Pharmacokinetics of Therapeutic Monoclonal Antibodies from Simple Allometry of Monkey Data

Masataka Oitate, Noriko Masubuchi, Takashi Ito et al. · Drug Metabolism and Pharmacokinetics · 2011 · 80 citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Identification and Therapeutic Targeting of GPR20, Selectively Expressed in Gastrointestinal Stromal Tumors, with DS-6157a, a First-in-Class Antibody–Drug Conjugate

Kenji Iida, Amr H. Abdelhamid Ahmed, Akiko Kawano Nagatsuma et al. · Cancer Discovery · 2021 · 50 citations

Medicine, Oncology, Pharmacology +17

A novel Menin-MLL1 inhibitor, DS-1594a, prevents the progression of acute leukemia with rearranged MLL1 or mutated NPM1

Masashi Numata, Noriyasu Haginoya, Machiko Shiroishi et al. · Cancer Cell International · 2023 · 29 citations · Full text

Medicine, Oncology, Pharmacology +13

Evaluation of the Usefulness of Breast Cancer Resistance Protein (BCRP) Knockout Mice and BCRP Inhibitor-Treated Monkeys to Estimate the Clinical Impact of BCRP Modulation on the Pharmacokinetics of BCRP Substrates

Tsuyoshi Karibe, Rie Hagihara-Nakagomi, Kōji Abe et al. · Pharmaceutical Research · 2014 · 28 citations

Medicine, Pharmacokinetics, Pharmacology +8