Sowmya Iyer

In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates

Kiran Musunuru, Alexandra C. Chadwick, Taiji Mizoguchi et al. · Nature · 2021 · 713 citations

Knockout Mouse, Genetics, Genetic Engineering +8

Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors

Julian Grünewald, Ronghao Zhou, Sara P. Garcia et al. · Nature · 2019 · 651 citations · Full text

Rna Processing, Genetics, Molecular Biology +6

CRISPR C-to-G base editors for inducing targeted DNA transversions in human cells

Ibrahim Cagri Kurt, Ronghao Zhou, Sowmya Iyer et al. · Nature Biotechnology · 2020 · 552 citations · Full text

Human Cells, Natural Sciences, Synthetic Biology +11

Cancer-Specific Retargeting of BAF Complexes by a Prion-like Domain

Gaylor Boulay, Gabriel J. Sandoval, Nicolò Riggi et al. · Cell · 2017 · 472 citations · Full text

Baf Complexes, Natural Sciences, Molecular Biology +4

CRISPR DNA base editors with reduced RNA off-target and self-editing activities

Julian Grünewald, Ronghao Zhou, Sowmya Iyer et al. · Nature Biotechnology · 2019 · 333 citations

Engineering, Cell Modification, Reduced Rna Off-target +11