John Hamre

Targeting Glycolysis through Inhibition of Lactate Dehydrogenase Impairs Tumor Growth in Preclinical Models of Ewing Sarcoma

Choh Yeung, Anna E. Gibson, Sameer H. Issaq et al. · Cancer Research · 2019 · 123 citations · Full text

Examining the Protective Role of ErbB2 Modulation in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Sandy Eldridge, Liang Guo, Jodie Mussio et al. · Toxicological Sciences · 2014 · 48 citations · Full text

Cardiac Muscle, Heart Failure, Cardiac Regeneration +23

Multiparametric Image Analysis of Rat Dorsal Root Ganglion Cultures to Evaluate Peripheral Neuropathy-Inducing Chemotherapeutics

Liang Guo, John Hamre, Sandy Eldridge et al. · Toxicological Sciences · 2016 · 34 citations · Full text

Peripheral Nerve Injury, Neuropathic Pain, Peripheral Nerve +22

Predicting Genetic Variation Severity Using Machine Learning to Interpret Molecular Simulations

Matthew McCoy, John Hamre, Dmitri K. Klimov et al. · Biophysical Journal · 2020 · 23 citations · Full text

Genetic Analysis, Functional Genomics, Engineering +13

Machine learning-based prediction of drug and ligand binding in BCL-2 variants through molecular dynamics

John Hamre, Dmitri K. Klimov, Matthew McCoy et al. · Computers in Biology and Medicine · 2021 · 14 citations · Full text