Concepedia

Author

Michaela Nekardová

Charles UniversityORCID

Also Known As

Michaela Nekardova, Michaela Nekardová

12

Publications

232

Citations

10

H-Index

8

Concepts

All Affiliations

Charles UniversityCzech Academy of Sciences, Institute of Organic Chemistry and BiochemistryCzech Academy of Sciences, Institute of PhysiologyCzech Academy of SciencesPalacký University Olomouc
MN

About

Michaela Nekardová is an author at Charles University specializing in drug discovery, medicinal chemistry, and natural sciences.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

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2

Natural Sciences

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3

Biochemistry

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Pharmacology

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26

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Drug Discovery

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Michaela Nekardová

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10

Publications

229

Citations

10

H-Index

YearCitations

Preferential Inhibition of Tonically over Phasically Activated NMDA Receptors by Pregnane Derivatives

Vojtěch Vyklický, Tereza Smejkalová, Barbora Hrčka Krausová,

Journal of Neuroscience

2016

48

A New Class of Potent<i>N</i>-Methyl-<scp>d</scp>-Aspartate Receptor Inhibitors: Sulfated Neuroactive Steroids with Lipophilic D-Ring Modifications

Eva Kudová, Hana Chodounská, Barbora Slavı́ková,

Journal of Medicinal Chemistry

2015

32

Positive Modulators of the<i>N</i>-Methyl-<scp>d</scp>-aspartate Receptor: Structure–Activity Relationship Study of Steroidal 3-Hemiesters

Barbora Hrčka Krausová, Barbora Slavı́ková, Michaela Nekardová,

Journal of Medicinal Chemistry

2018

27

3,5,7-Substituted Pyrazolo[4,3-<i>d</i>]pyrimidine Inhibitors of Cyclin-Dependent Kinases and Their Evaluation in Lymphoma Models

Radek Jorda, Libor Havlı́ček, Antonín Šturc,

Journal of Medicinal Chemistry

2019

27

Physicochemical and biological properties of novel amide-based steroidal inhibitors of NMDA receptors

Santosh Kumar Adla, Barbora Slavı́ková, Markéta Šmídková,

Steroids

2016

26

Neurosteroid-like Inhibitors of<i>N</i>-Methyl-<scp>d</scp>-aspartate Receptor: Substituted 2-Sulfates and 2-Hemisuccinates of Perhydrophenanthrene

Barbora Slavı́ková, Hana Chodounská, Michaela Nekardová,

Journal of Medicinal Chemistry

2016

17

Structural Basis of the Interaction of Cyclin‐Dependent Kinase 2 with Roscovitine and Its Analogues Having Bioisosteric Central Heterocycles

Michaela Nekardová, Ladislava Vymětalová, Prashant Khirsariya,

ChemPhysChem

2017

16

Synthetic testosterone derivatives modulate rat P2X2 and P2X4 receptor channel gating

Sonja Sivcev, Barbora Slavı́ková, Marian Rupert,

Journal of Neurochemistry

2019

15

Strong Inhibitory Effect, Low Cytotoxicity and High Plasma Stability of Steroidal Inhibitors of N-Methyl-D-Aspartate Receptors With C-3 Amide Structural Motif

Santosh Kumar Adla, Barbora Slavı́ková, Hana Chodounská,

Frontiers in Pharmacology

2018

11

Knowledge-based prediction of DNA hydration using hydrated dinucleotides as building blocks

Lada Biedermannová, Jiří Černý, Michal Malý,

Acta Crystallographica Section D Structural Biology

2022

10

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