Wing Lam

Reproducing human and cross-species drug toxicities using a Liver-Chip

Kyung‐Jin Jang, Monicah A. Otieno, Janey Ronxhi et al. · Science Translational Medicine · 2019 · 451 citations

Can In Vitro Metabolism-Dependent Covalent Binding Data Distinguish Hepatotoxic from Nonhepatotoxic Drugs? An Analysis Using Human Hepatocytes and Liver S-9 Fraction

Jonathon N. Bauman, Joan M. Kelly, Sakambari Tripathy et al. · Chemical Research in Toxicology · 2009 · 133 citations

Pathology, Vitro Covalent, Toxicological Mechanism +21

In electrospray ionization source hydrogen/deuterium exchange LC-MS and LC-MS/MS for characterization of metabolites

Wing Lam, Ragu Ramanathan · Journal of the American Society for Mass Spectrometry · 2002 · 122 citations

Bioorganic Chemistry, Chemical Analysis, Biological Mass Spectrometry +20

Fasiglifam (TAK-875): Mechanistic Investigation and Retrospective Identification of Hazards for Drug Induced Liver Injury

Monicah A. Otieno, Jan Snoeys, Wing Lam et al. · Toxicological Sciences · 2017 · 81 citations · Full text

Pharmacotherapy, Toxicological Mechanism, Oxidative Stress +20

Application of stable isotope labeled glutathione and rapid scanning mass spectrometers in detecting and characterizing reactive metabolites

Abdul Mutlib, Wing Lam, Jim Atherton et al. · Rapid Communications in Mass Spectrometry · 2005 · 76 citations

Metabolomic Profiling, Gas Chromatography, Bioanalysis +18