Jan Snoeys

Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

Catherine C. Bell, Delilah Hendriks, Sabrina Moro et al. · Scientific Reports · 2016 · 686 citations · Full text

Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling

David C. Hay, Judy Fletcher, Catherine Payne et al. · Proceedings of the National Academy of Sciences · 2008 · 427 citations · Full text

Human Liver Development, Wnt Signaling, Organ Development +19

Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study

Catherine C. Bell, Anita C. A. Dankers, Volker M. Lauschke et al. · Toxicological Sciences · 2018 · 297 citations · Full text

Tissue Engineering, Engineering, Sandwich Configuration +20

The utility of HepG2 cells to identify direct mitochondrial dysfunction in the absence of cell death

Laleh Kamalian, Amy E. Chadwick, Mark Bayliss et al. · Toxicology in Vitro · 2015 · 150 citations · Full text

Mitophagy, Mitochondrial Dysfunction, Apoptosis +24

Amino acid levels determine metabolism and CYP450 function of hepatocytes and hepatoma cell lines

Ruben Boon, Manoj Kumar, Tine Tricot et al. · Nature Communications · 2020 · 124 citations · Full text