Simon J. Clark

Shiga Toxin Activates Complement and Binds Factor H: Evidence for an Active Role of Complement in Hemolytic Uremic Syndrome

Dorothea Orth‐Höller, Abdul Basit Khan, Asma Naim et al. · The Journal of Immunology · 2009 · 209 citations · Full text

Life Sciences, Infectious Diseases, Pathobiology +17

Impaired Binding of the Age-related Macular Degeneration-associated Complement Factor H 402H Allotype to Bruch's Membrane in Human Retina

Simon J. Clark, Rahat Perveen, Svetlana Hakobyan et al. · Journal of Biological Chemistry · 2010 · 186 citations · Full text

Medicine, Genetics, Ophthalmology +17

Structural basis for complement factor H–linked age-related macular degeneration

Beverly E. Prosser, Steven Johnson, Pietro Roversi et al. · The Journal of Experimental Medicine · 2007 · 184 citations · Full text

Medicine, Genetics, Ophthalmology +17

His-384 Allotypic Variant of Factor H Associated with Age-related Macular Degeneration Has Different Heparin Binding Properties from the Non-disease-associated Form

Simon J. Clark, Victoria Ann Higman, Barbara Mulloy et al. · Journal of Biological Chemistry · 2006 · 183 citations · Full text

Medicine, Molecular Biology, Ophthalmology +15

Tissue-Specific Host Recognition by Complement Factor H Is Mediated by Differential Activities of Its Glycosaminoglycan-Binding Regions

Simon J. Clark, Liam A. Ridge, Andrew P. Herbert et al. · The Journal of Immunology · 2013 · 148 citations · Full text

Life Sciences, Immunology, Molecular Biology +17