Frances Belmonte

ErbB2 overexpression upregulates antioxidant enzymes, reduces basal levels of reactive oxygen species, and protects against doxorubicin cardiotoxicity

Frances Belmonte, Samarjit Das, Polina Sysa‐Shah et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2015 · 109 citations · Full text

Doxorubicin Cardiotoxicity, Heart Failure, Lipid Peroxidation +18

LRRK2 G2019S-induced mitochondrial DNA damage is LRRK2 kinase dependent and inhibition restores mtDNA integrity in Parkinson’s disease

Evan H. Howlett, Nicholas O. Jensen, Frances Belmonte et al. · Human Molecular Genetics · 2017 · 102 citations · Full text

Mitophagy, Genetics, Cell Death +16

Digital PCR methods improve detection sensitivity and measurement precision of low abundance mtDNA deletions

Frances Belmonte, James Martin, Kristin Frescura et al. · Scientific Reports · 2016 · 85 citations · Full text

Genetics, Dna Analysis, Digital Pcr Methods +22

Cardiac-Specific Over-Expression of Epidermal Growth Factor Receptor 2 (ErbB2) Induces Pro-Survival Pathways and Hypertrophic Cardiomyopathy in Mice

Polina Sysa‐Shah, Xu Yi, Xin Guo et al. · PLoS ONE · 2012 · 63 citations · Full text

Bidirectional cross-regulation between ErbB2 and β-adrenergic signalling pathways

Polina Sysa‐Shah, Carlo G. Tocchetti, Manveen K. Gupta et al. · Cardiovascular Research · 2015 · 48 citations · Full text