Piétro Scalfaro

The non‐immunosuppressive cyclosporin DEBIO‐025 is a potent inhibitor of hepatitis C virus replication in vitro†

Jan Paeshuyse, Artur Kaul, Erik De Clercq et al. · Hepatology · 2006 · 276 citations · Full text

Life Sciences, Microbiology, Molecular Biology +16

The cyclophilin inhibitor Debio-025 shows potent anti–hepatitis C effect in patients coinfected with hepatitis C and human immunodeficiency virus

Robert Flisiak, Andrzej Horban, Philippe Gallay et al. · Hepatology · 2008 · 223 citations

Pharmacy, Pharmacology, Pharmacotherapy +14

The cyclophilin inhibitor Debio 025 combined with PEG IFNα2a significantly reduces viral load in treatment-naïve hepatitis C patients #

Robert Flisiak, S.V. Feinman, Maciej Jabłkowski et al. · Hepatology · 2009 · 222 citations · Full text

Pharmacy, Pharmacology, Pharmacotherapy +16

Inhibition of mitochondrial permeability transition improves functional recovery and reduces mortality following acute myocardial infarction in mice

Ludovic Gomez, Hélène Thibault, Adbdallah Gharib et al. · American Journal of Physiology-Heart and Circulatory Physiology · 2007 · 184 citations

Life Sciences, Cardiology, Pharmacology +17

Inhibition of Human Immunodeficiency Virus Type 1 Replication in Human Cells by Debio-025, a Novel Cyclophilin Binding Agent

Roger G. Ptak, Philippe Gallay, Dirk Jochmans et al. · Antimicrobial Agents and Chemotherapy · 2008 · 114 citations · Full text

Medicine, Infectious Diseases, Pharmacology +12