Nancy Leal

STI571 prevents apoptosis, tau phosphorylation and behavioural impairments induced by Alzheimer's β-amyloid deposits

Gonzalo I. Cancino, Enrique M. Toledo, Nancy Leal et al. · Brain · 2008 · 144 citations · Full text

Activation of the neuronal c-Abl tyrosine kinase by amyloid-β-peptide and reactive oxygen species

Alejandra Álvarez, Pablo C. Sandoval, Nancy Leal et al. · Neurobiology of Disease · 2004 · 125 citations · Full text

Neurodegenerative Diseases, Molecular Neuroscience, Signal Transduction +9

EphA4 Activation of c-Abl Mediates Synaptic Loss and LTP Blockade Caused by Amyloid-β Oligomers

Lina Moitoso de Vargas, Nancy Leal, Lisbell D. Estrada et al. · PLoS ONE · 2014 · 85 citations · Full text

Synaptic Transmission, Ltp Blockade, Epha4 Activation +22

High-Frequency Field Stimulation of Primary Neurons Enhances Ryanodine Receptor-Mediated Ca ²⁺ Release and Generates Hydrogen Peroxide, Which Jointly Stimulate NF-κB Activity

D. Riquelme, Álvaro Álvarez, Nancy Leal et al. · Antioxidants and Redox Signaling · 2010 · 55 citations · Full text

c-Abl Inhibition Activates TFEB and Promotes Cellular Clearance in a Lysosomal Disorder

Pablo S. Contreras, Pablo Tapía, Lila González-Hódar et al. · iScience · 2020 · 43 citations · Full text