Dennis J. Hartigan-O’Connor

Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade

Ziming Wang, Ethan G. Aguilar, Jesus I. Luna et al. · Nature Medicine · 2018 · 806 citations

Obesity, Cancer Immunosurveillance, Pd-1 Checkpoint Blockade +10

Homeobox gene Nkx2.2 and specification of neuronal identity by graded Sonic hedgehog signalling

James Briscoe, Lori Sussel, Palle Serup et al. · Nature · 1999 · 785 citations

Knockout Mouse, Neuronal Identity, Developmental Biology +11

Mice lacking the homeodomain transcription factor Nkx2.2 have diabetes due to arrested differentiation of pancreatic β cells

Lori Sussel, Julie Kalamaras, Dennis J. Hartigan-O’Connor et al. · Development · 1998 · 625 citations

Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cells

Dennis J. Hartigan-O’Connor, Chungkee Poon, Elizabeth Sinclair et al. · Journal of Immunological Methods · 2006 · 282 citations

Inflammation, Consistent Identification, Live Cells +12

HIV latency is reversed by ACSS2-driven histone crotonylation

Guochun Jiang, Don X. Nguyen, Nancie M. Archin et al. · Journal of Clinical Investigation · 2018 · 162 citations · Full text

Histone Modifications, Chromatin, Viral Latency +15