Pin‐Kuang Lai

Machine learning prediction of antibody aggregation and viscosity for high concentration formulation development of protein therapeutics

Pin‐Kuang Lai, Austin Gallegos, Neil Mody et al. · mAbs · 2022 · 81 citations · Full text

Engineering, Machine Learning, Biomedical Engineering +25

Machine Learning Applied to Determine the Molecular Descriptors Responsible for the Viscosity Behavior of Concentrated Therapeutic Antibodies

Pin‐Kuang Lai, Amendra Fernando, Theresa K. Cloutier et al. · Molecular Pharmaceutics · 2021 · 71 citations

Pharmaceutical Science, Immunocytochemical Technique, Engineering +23

Coarse-Grained Modeling of Protein Second Osmotic Virial Coefficients: Sterics and Short-Ranged Attractions

Alexander Grünberger, Pin‐Kuang Lai, Marco A. Blanco et al. · The Journal of Physical Chemistry B · 2012 · 67 citations

Biophysical Modeling, Protein Assembly, Biomolecular Structure Prediction +16

Rapid determination of entropy and free energy of mixtures from molecular dynamics simulations with the two-phase thermodynamic model

Pin‐Kuang Lai, Chieh‐Ming Hsieh, Shiang‐Tai Lin · Physical Chemistry Chemical Physics · 2012 · 56 citations

Machine Learning Feature Selection for Predicting High Concentration Therapeutic Antibody Aggregation

Pin‐Kuang Lai, Amendra Fernando, Theresa K. Cloutier et al. · Journal of Pharmaceutical Sciences · 2020 · 45 citations

Engineering, Machine Learning, Data Science +6