Inhibitory Inputs from Rostromedial Tegmental Neurons Regulate Spontaneous Activity of Midbrain Dopamine Cells and Their Responses to Drugs of Abuse

Salvatore Lecca, Miriam Melis, Antonio Luchicchi, +2

Neuropsychopharmacology

Neurobiological MechanismPsychiatryTheir ResponsesNeuroanatomyMedicine +11

Rescue of GABAB and GIRK function in the lateral habenula by protein phosphatase 2A inhibition ameliorates depression-like phenotypes in mice

Salvatore Lecca, Assunta Pelosi, Anna Tchenio, +4

Nature Medicine

Molecular NeuroscienceSignal TransductionMolecular PhysiologyGirk FunctionProtein Phosphatase 2A +11

Aversive stimuli drive hypothalamus-to-habenula excitation to promote escape behavior

Salvatore Lecca, Frank J. Meye, Massimo Trusel, +6

eLife

Effects of Drugs of Abuse on Putative Rostromedial Tegmental Neurons, Inhibitory Afferents to Midbrain Dopamine Cells

Salvatore Lecca, Miriam Melis, Antonio Luchicchi, +4

Neuropsychopharmacology

Psychoactive DrugPsychiatryNeuroanatomyAddictionMidbrain Dopamine Cells +10

Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments

Francesco Petrelli, Glenn Dallérac, Luca Pucci, +17

Molecular Psychiatry

Blockade of Nicotine Reward and Reinstatement by Activation of Alpha-Type Peroxisome Proliferator-Activated Receptors

Paola Mascia, Marco Pistis, Zuzana Justinová, +13

Biological Psychiatry

Tobacco ControlFunctional SelectivityAddictionMedicinePhysiology +7

Limiting habenular hyperactivity ameliorates maternal separation-driven depressive-like symptoms

Anna Tchenio, Salvatore Lecca, Kristina Valentinova, +1

Nature Communications

Maternal Immune Activation Disrupts Dopamine System in the Offspring

Antonio Luchicchi, Salvatore Lecca, Miriam Melis, +7

The International Journal of Neuropsychopharmacology

Cocaine-evoked negative symptoms require AMPA receptor trafficking in the lateral habenula

Frank J. Meye, Kristina Valentinova, Salvatore Lecca, +8

Nature Neuroscience

NeurophysiologyNeuroanatomyPhysiologyNeurotransmitterNeuropharmacology +11

Punishment-Predictive Cues Guide Avoidance through Potentiation of Hypothalamus-to-Habenula Synapses

Massimo Trusel, Alvaro Nuno‐Perez, Salvatore Lecca, +7

Neuron

NeuropsychologyBehavioral NeuroscienceInhibitory ProcessAffective NeuroscienceNeuroscience +5