Leighton H. Daigh

Clinical CDK4/6 inhibitors induce selective and immediate dissociation of p21 from cyclin D-CDK4 to inhibit CDK2

Lindsey R. Pack, Leighton H. Daigh, Mingyu Chung et al. · Nature Communications · 2021 · 98 citations · Full text

Stress-mediated exit to quiescence restricted by increasing persistence in CDK4/6 activation

Hee Won Yang, Steven D. Cappell, Ariel Jaimovich et al. · eLife · 2020 · 91 citations · Full text

Cell Proliferation, Cell Cycle, Cdk2 Activity +16

Stochastic Endogenous Replication Stress Causes ATR-Triggered Fluctuations in CDK2 Activity that Dynamically Adjust Global DNA Synthesis Rates

Leighton H. Daigh, Chad Liu, Mingyu Chung et al. · Cell Systems · 2018 · 53 citations · Full text

Chromatin, Genome Instability, Cell Regulation +10

Altered G1 signaling order and commitment point in cells proliferating without CDK4/6 activity

Chad Liu, Yumi Konagaya, Mingyu Chung et al. · Nature Communications · 2020 · 47 citations · Full text

Hepatic compartmentalization of exhausted and regulatory cells in <scp>HIV</scp>/<scp>HCV</scp>‐coinfected patients

Lisa Feldman Barrett, Nirupma Trehanpati, Seerat Poonia et al. · Journal of Viral Hepatitis · 2014 · 14 citations