Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers

Yuan Lin, Haipeng Zhang, Jiankai Liang, +20

Proceedings of the National Academy of Sciences

Synthetic VirologyImmunologyPathologySelective Oncolytic VirusZap-defective Human Cancers +15

The Anti-Warburg Effect Elicited by the cAMP-PGC1α Pathway Drives Differentiation of Glioblastoma Cells into Astrocytes

Fan Xing, Yizhao Luan, Jing Cai, +30

Cell Reports

Targeting VCP enhances anticancer activity of oncolytic virus M1 in hepatocellular carcinoma

Haipeng Zhang, Kai Li, Yuan Lin, +16

Science Translational Medicine

Vcp EnhancesImmunologyImmunotherapeuticsOncolytic Virus M1Antiviral Drug +16

Naturally Existing Oncolytic Virus M1 Is Nonpathogenic for the Nonhuman Primates After Multiple Rounds of Repeated Intravenous Injections

Haipeng Zhang, Yuan Lin, Kai Li, +30

Human Gene Therapy

RETRACTED ARTICLE: DNA-PK inhibition synergizes with oncolytic virus M1 by inhibiting antiviral response and potentiating DNA damage

Xiao Xiao, Jiankai Liang, Chunlong Huang, +20

Nature Communications

Intravenous injection of the oncolytic virus M1 awakens antitumor T cells and overcomes resistance to checkpoint blockade

Yang Liu, Jing Cai, Wenfeng Liu, +10

Cell Death and Disease

Identification of the receptor of oncolytic virus M1 as a therapeutic predictor for multiple solid tumors

Deli Song, Xudong Jia, Xincheng Liu, +25

Signal Transduction and Targeted Therapy

Necroptotic virotherapy of oncolytic alphavirus M1 cooperated with Doxorubicin displays promising therapeutic efficacy in TNBC

Jiayu Zhang, Ying Liu, Jingyi Tan, +16

Oncogene

Molecular VirologyDoxorubicin DisplaysOncolytic Alphavirus M1ImmunologyViral Pathogenesis +8

Activation of Cyclic Adenosine Monophosphate Pathway Increases the Sensitivity of Cancer Cells to the Oncolytic Virus M1

Kai Li, Haipeng Zhang, Jianguang Qiu, +22

Molecular Therapy

Selective replication of oncolytic virus M1 results in a bystander killing effect that is potentiated by Smac mimetics

Jing Cai, Yuan Lin, Haipeng Zhang, +4

Proceedings of the National Academy of Sciences