Florent X. Smit

Primary Fibril Nucleation of Aggregation Prone Tau Fragments <i>PHF6</i> and <i>PHF6</i>*

Florent X. Smit, Jurriaan A. Luiken, Peter G. Bolhuis · The Journal of Physical Chemistry B · 2016 · 59 citations · Full text

Life Sciences, Biochemistry, Biophysics +17

Enhanced agonist residence time, internalization rate and signalling of the GIP receptor variant [E354Q] facilitate receptor desensitization and long‐term impairment of the GIP system

M Gabe, Wijnand J. C. van der Velden, Sarina Gadgaard et al. · Basic & Clinical Pharmacology & Toxicology · 2019 · 52 citations · Full text

Medicine, Endocrinology, Pharmacology +17

GLP-1 Val8: A Biased GLP-1R Agonist with Altered Binding Kinetics and Impaired Release of Pancreatic Hormones in Rats

Wijnand J. C. van der Velden, Florent X. Smit, C. Christiansen et al. · ACS Pharmacology & Translational Science · 2021 · 33 citations · Full text

Medicine, Molecular Biology, Pharmacology +17

Optimization of Particle Transfers in the Gibbs Ensemble for Systems with Strong and Directional Interactions Using CBMC, CFCMC, and CB/CFCMC

Ariana Torres‐Knoop, Nicholas C. Burtch, Ali Poursaeidesfahani et al. · The Journal of Physical Chemistry C · 2016 · 23 citations

Natural Sciences, Chemistry, Physics +17

Investigating GIPR (ant)agonism: A structural analysis of GIP and its receptor

Florent X. Smit, Wijnand J. C. van der Velden, Hüsün Sheyma Kizilkaya et al. · Structure · 2021 · 22 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12