Christine K. Maurer

Antibiotic-free nanotherapeutics: Ultra-small, mucus-penetrating solid lipid nanoparticles enhance the pulmonary delivery and anti-virulence efficacy of novel quorum sensing inhibitors

Noha Nafee, Ayman Husari, Christine K. Maurer et al. · Journal of Controlled Release · 2014 · 202 citations · Full text

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +17

Validation of PqsD as an Anti-biofilm Target in Pseudomonas aeruginosa by Development of Small-Molecule Inhibitors

Michael P. Storz, Christine K. Maurer, Christina Zimmer et al. · Journal of the American Chemical Society · 2012 · 123 citations

Life Sciences, Microbiology, Pharmacology +17

Discovery of Antagonists of PqsR, a Key Player in 2-Alkyl-4-quinolone-Dependent Quorum Sensing in Pseudomonas aeruginosa

Cenbin Lu, Benjamin Kirsch, Christina Zimmer et al. · Chemistry & Biology · 2012 · 121 citations · Full text

Life Sciences, Microbiology, Bacteriology +13

Overcoming the Unexpected Functional Inversion of a PqsR Antagonist in <i>Pseudomonas aeruginosa</i> : An In Vivo Potent Antivirulence Agent Targeting <i>pqs</i> Quorum Sensing

Cenbin Lu, Christine K. Maurer, Benjamin Kirsch et al. · Angewandte Chemie International Edition · 2013 · 97 citations · Full text

Life Sciences, Microbiology, Pharmacology +15

Identification of Small-Molecule Antagonists of the <i>Pseudomonas aeruginosa</i> Transcriptional Regulator PqsR: Biophysically Guided Hit Discovery and Optimization

Tobias Klein, Claudia Henn, Johannes C. de Jong et al. · ACS Chemical Biology · 2012 · 73 citations

Life Sciences, Microbiology, Pharmacology +17