Joseph A. Toonen

NF1 mutation drives neuronal activity-dependent initiation of optic glioma

Yuan Pan, Jared Hysinger, Tara Barron et al. · Nature · 2021 · 231 citations · Full text

Neuro-oncology, Molecular Neuroscience, Glioma +8

RNA Sequencing of Tumor-Associated Microglia Reveals Ccl5 as a Stromal Chemokine Critical for Neurofibromatosis-1 Glioma Growth

Anne C. Solga, Winnie W. Pong, Keunyoung Kim et al. · Neoplasia · 2015 · 96 citations · Full text

Akt- or MEK-mediated mTOR inhibition suppresses Nf1 optic glioma growth

Aparna Kaul, Joseph A. Toonen, Patrick J. Cimino et al. · Neuro-Oncology · 2014 · 91 citations · Full text

<i>NF1</i>germline mutation differentially dictates optic glioma formation and growth in neurofibromatosis-1

Joseph A. Toonen, Corina Anastasaki, Laura J. Smithson et al. · Human Molecular Genetics · 2016 · 73 citations · Full text

Estrogen activation of microglia underlies the sexually dimorphic differences in <i>Nf1</i> optic glioma–induced retinal pathology

Joseph A. Toonen, Anne C. Solga, Yu Ma et al. · The Journal of Experimental Medicine · 2016 · 65 citations · Full text

Retinal Therapies, Optic Nerve, Estrogen Activation +17