Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson’s disease

Sonja Kriks, Jaewon Shim, Jinghua Piao, +13

Nature

Neurodegenerative DiseasesNeurobiology Of DiseaseSynaptic SignalingAnimal ModelsStem Cell Research +10

Pharmacological Rescue of Mitochondrial Deficits in iPSC-Derived Neural Cells from Patients with Familial Parkinson’s Disease

Oliver Cooper, Hyemyung Seo, Shaida A. Andrabi, +36

Science Translational Medicine

Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

Akiko Hayashi‐Takagi, Manabu Takaki, Saurav Seshadri, +15

Nature Neuroscience

Synaptic PlasticityMolecular NeuroscienceMedicineSynaptic TransmissionPsychiatric Genetics +8

Kalirin-7 Controls Activity-Dependent Structural and Functional Plasticity of Dendritic Spines

Zhong Xie, Deepak P. Srivastava, Huzefa Photowala, +6

Neuron

Synaptic PlasticityDendritic SpinesMolecular NeuroscienceMolecular PhysiologyNeuroanatomy +10

Peroxynitrite mediates neurotoxicity of amyloid beta-peptide1-42- and lipopolysaccharide-activated microglia.

Zhong Xie, Min Wei, Todd E. Morgan, +4

PubMed

Nitric OxideLipid PeroxidationCell DeathRedox BiologyOxidative Stress +15

M4 Muscarinic Receptor Signaling Ameliorates Striatal Plasticity Deficits in Models of L-DOPA-Induced Dyskinesia

Weixing Shen, Joshua L. Plotkin, Veronica Francardo, +12

Neuron

Synaptic PlasticityMedicineNeurotransmitterNeuropharmacologyNeurology +5

Peroxynitrite Mediates Neurotoxicity of Amyloid β-Peptide_1–42- and Lipopolysaccharide-Activated Microglia

Zhong Xie, Min Wei, Todd E. Morgan, +4

Journal of Neuroscience

Nitric OxideCell DeathPeroxynitrite DonorRedox BiologyFerroptosis +15

Calcium Entry and  -Synuclein Inclusions Elevate Dendritic Mitochondrial Oxidant Stress in Dopaminergic Neurons

Dilyan I. Dryanovski, Jaime N. Guzmán, Zhong Xie, +6

Journal of Neuroscience

The mosaic of brain glial hyperactivity during normal ageing and its attenuation by food restriction

Todd E. Morgan, Zhong Xie, Sara K. Goldsmith, +7

Neuroscience

Normal AgeingNeuropsychologyAlzheimer's DiseaseAgingBrain Function +10

Impaired TrkB Receptor Signaling Underlies Corticostriatal Dysfunction in Huntington’s Disease

Joshua L. Plotkin, Michelle Day, Jayms D. Peterson, +12

Neuron