Darrin Dutcher

Changes in gene expression in the intact human heart. Downregulation of alpha-myosin heavy chain in hypertrophied, failing ventricular myocardium.

Brian D. Lowes, Wayne Minobe, William T. Abraham et al. · Journal of Clinical Investigation · 1997 · 503 citations · Full text

Medicine, Cardiology, Physiology +11

Selective Downregulation of the Angiotensin II AT₁-Receptor Subtype in Failing Human Ventricular Myocardium

Koji Asano, Darrin Dutcher, J. David Port et al. · Circulation · 1997 · 168 citations

Medicine, Cardiology, Pharmacology +12

Coordinate Changes in Myosin Heavy Chain Isoform Gene Expression Are Selectively Associated With Alterations in Dilated Cardiomyopathy Phenotype

William T. Abraham, Edward M. Gilbert, Brian D. Lowes et al. · Molecular Medicine · 2002 · 106 citations · Full text

Life Sciences, Cardiology, Genetics +16

Spirocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitors: From Hit to Lowering of Cerebrospinal Fluid (CSF) Amyloid β in a Higher Species

Kevin W. Hunt, Adam W. Cook, Ryan J. Watts et al. · Journal of Medicinal Chemistry · 2013 · 58 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Differential Regulation of Cardiac Angiotensin Converting Enzyme Binding Sites and AT₁Receptor Density in the Failing Human Heart

Lawrence S. Zisman, Koji Asano, Darrin Dutcher et al. · Circulation · 1998 · 57 citations

Medicine, Pharmacology, Physiology +15