Pathum M. Weerawarna

Design and Mechanism of (<i>S</i>)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent γ-Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Addiction

Jose I. Juncosa, Kenji Takaya, Hoang V. Le et al. · Journal of the American Chemical Society · 2018 · 69 citations

Life Sciences, Neuroscience, Pharmacology +17

Potent inhibition of norovirus 3CL protease by peptidyl α-ketoamides and α-ketoheterocycles

Sivakoteswara Rao Mandadapu, Pathum M. Weerawarna, Mallikarjuna Reddy Gunnam et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 60 citations · Full text

Life Sciences, Biochemistry, Microbiology +15

Structure-Guided Design and Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease. Structure–Activity Relationships and Biochemical, X-ray Crystallographic, Cell-Based, and In Vivo Studies

Anushka C. Galasiti Kankanamalage, Yunjeong Kim, Pathum M. Weerawarna et al. · Journal of Medicinal Chemistry · 2015 · 54 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Macrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus

Sivakoteswara Rao Mandadapu, Pathum M. Weerawarna, Allan M. Prior et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 47 citations · Full text

Pharmacy, Infectious Diseases, Medicinal Chemistry +14

Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: Structural, biochemical, spectroscopic, and antiviral studies

Pathum M. Weerawarna, Yunjeong Kim, Anushka C. Galasiti Kankanamalage et al. · European Journal of Medicinal Chemistry · 2016 · 36 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17