Zac Yates

Succinimide formation at Asn 55 in the complementarity determining region of a recombinant monoclonal antibody IgG1 heavy chain

Boxu Yan, Sean Steen, David M. Hambly et al. · Journal of Pharmaceutical Sciences · 2009 · 168 citations

Succinimide Formation, Asn 55, Immunocytochemical Technique +12

Analysis of post-translational modifications in recombinant monoclonal antibody IgG1 by reversed-phase liquid chromatography/mass spectrometry

Boxu Yan, John Valliere‐Douglass, Lowell J. Brady et al. · Journal of Chromatography A · 2007 · 100 citations

Post-translational Modifications, Bioanalysis, Mass Spectrometry +9

Human IgG1 Hinge Fragmentation as the Result of H2O2-mediated Radical Cleavage

Boxu Yan, Zac Yates, Alain Balland et al. · Journal of Biological Chemistry · 2009 · 47 citations · Full text

Hinge Cleavage, Glycobiology, Molecular Biology +19

Optimization of CE-SDS Method for Antibody Separation Based on Multi-Users Experimental Practices

Mei Han, D.H.T. Phan, Nancy S. Nightlinger et al. · Chromatographia · 2006 · 32 citations

Engineering, Separation Science, Antibody Separation +13

Histidine Residue Mediates Radical-induced Hinge Cleavage of Human IgG1

Zac Yates, Gunasekaran Kannan, Zhonghua Hu et al. · Journal of Biological Chemistry · 2010 · 31 citations · Full text

Hinge Cleavage, Protein Assembly, Molecular Biology +16