Susumu Tanimura

Targeting the ERK signaling pathway as a potential treatment for insulin resistance and type 2 diabetes

Kei-ichi Ozaki, Midori Awazu, Mayuko Tamiya et al. · American Journal of Physiology-Endocrinology and Metabolism · 2016 · 171 citations · Full text

Life Sciences, Molecular Biology, Pharmacology +17

Extracellular Signal–Regulated Kinase Inhibition Slows Disease Progression in Mice with Polycystic Kidney Disease

Sayu Omori, Mariko Hida, Hisayo Fujita et al. · Journal of the American Society of Nephrology · 2006 · 153 citations

Medicine, Pathobiology, Pathology +15

Blockade of the Extracellular Signal-regulated Kinase Pathway Induces Marked G1 Cell Cycle Arrest and Apoptosis in Tumor Cells in Which the Pathway Is Constitutively Activated

Rika Hoshino, Susumu Tanimura, Kazushi Watanabe et al. · Journal of Biological Chemistry · 2001 · 130 citations · Full text

Life Sciences, Cell Biology, Oncology +17

ERK Pathway Positively Regulates the Expression of Sprouty Genes

Kei‐ichi Ozaki, Ryoji Kadomoto, Keita Asato et al. · Biochemical and Biophysical Research Communications · 2001 · 112 citations

Life Sciences, Cell Biology, Molecular Biology +11

GEF-H1 Mediates Tumor Necrosis Factor-α-induced Rho Activation and Myosin Phosphorylation

Eli Kakiashvili, Pam Speight, Faiza Waheed et al. · Journal of Biological Chemistry · 2009 · 111 citations · Full text

Life Sciences, Cell Biology, Pathology +17