Roy Hanna

Off-target effect of the BMI1 inhibitor PTC596 drives epithelial-mesenchymal transition in glioblastoma multiforme

Anthony Flamier, Mohamed Abdouh, Rimi Hamam et al. · npj Precision Oncology · 2020 · 96 citations · Full text

G-quadruplexes originating from evolutionary conserved L1 elements interfere with neuronal gene expression in Alzheimer’s disease

Roy Hanna, Anthony Flamier, A Barabino et al. · Nature Communications · 2021 · 69 citations · Full text

The Polycomb Repressive Complex 1 Protein BMI1 Is Required for Constitutive Heterochromatin Formation and Silencing in Mammalian Somatic Cells

Mohamed Abdouh, Roy Hanna, Jida El Hajjar et al. · Journal of Biological Chemistry · 2015 · 41 citations · Full text

Chromatin, Transcriptional Regulation, Chromatin Structure +15

Heterochromatic genome instability and neurodegeneration sharing similarities with Alzheimer’s disease in old Bmi1+/− mice

Jida El Hajjar, Wassim Chatoo, Roy Hanna et al. · Scientific Reports · 2019 · 39 citations · Full text

Sporadic Alzheimer, Old Bmi1+/− Mice, Genetics +18

Retinal development anomalies and cone photoreceptors degeneration upon Bmi1 deficiency

A Barabino, Vicky Plamondon, Mohamed Abdouh et al. · Development · 2016 · 34 citations · Full text

Ocular Disease, Genetics, Optogenetics +18