Concepedia

Author

Akello J. Agwa

The University of QueenslandORCID

Also Known As

A.J. Agwa, Akello Agwa, Akello J. Agwa, Akello Joanna Agwa, Joanna Akello Agwa

20

Publications

344

Citations

13

H-Index

18

Concepts

All Affiliations

The University of QueenslandUniversidade Federal de São PauloNational Institutes of HealthARC Centre of Excellence for Innovations in Peptide and Protein ScienceNational Cancer Institute
AJ

About

Akello J. Agwa is an author at The University of Queensland specializing in biomolecular engineering, molecular biology, and natural sciences.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Biomolecular Engineering

3

3

61

2

Natural Sciences

2

2

41

3

Biochemistry

2

2

69

4

Engineering

1

1

23

5

Medicine

1

1

46

Akello J. Agwa

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12

Publications

317

Citations

12

H-Index

YearCitations

Spider peptide toxin HwTx-IV engineered to bind to lipid membranes has an increased inhibitory potency at human voltage-gated sodium channel hNaV1.7

Akello J. Agwa, Nicole Lawrence, Evelyne Deplazes,

Biochimica et Biophysica Acta (BBA) - Biomembranes

2017

51

Gating modifier toxins isolated from spider venom: Modulation of voltage-gated sodium channels and the role of lipid membranes

Akello J. Agwa, Steve Peigneur, Chun Yuen Chow,

Journal of Biological Chemistry

2018

46

Fluorescence Imaging of Peripheral Nerves by a Na<sub>v</sub>1.7-Targeted Inhibitor Cystine Knot Peptide

Junior Gonzales, Paula Demétrio De Souza França, Yan Jiang,

Bioconjugate Chemistry

2019

31

Enzymatic Ligation of a Pore Blocker Toxin and a Gating Modifier Toxin: Creating Double-Knotted Peptides with Improved Sodium Channel Na<sub>V</sub>1.7 Inhibition

Hue N. T. Tran, Poanna Tran, Jennifer R. Deuis,

Bioconjugate Chemistry

2019

27

Pharmacological Inhibition of the Voltage-Gated Sodium Channel Na<sub>V</sub>1.7 Alleviates Chronic Visceral Pain in a Rodent Model of Irritable Bowel Syndrome

Yan Jiang, Joel Castro, Linda V. Blomster,

ACS Pharmacology & Translational Science

2021

25

Lengths of the C-Terminus and Interconnecting Loops Impact Stability of Spider-Derived Gating Modifier Toxins

Akello J. Agwa, Yen‐Hua Huang, David J. Craik,

Toxins

2017

23

Mapping the Molecular Surface of the Analgesic Na<sub>V</sub>1.7-Selective Peptide Pn3a Reveals Residues Essential for Membrane and Channel Interactions

Alexander Mueller, Zoltan Dekan, Quentin Kaas,

ACS Pharmacology & Translational Science

2020

23

Efficient Enzymatic Ligation of Inhibitor Cystine Knot Spider Venom Peptides: Using Sortase A To Form Double-Knottins That Probe Voltage-Gated Sodium Channel Na<sub>V</sub>1.7

Akello J. Agwa, Linda V. Blomster, David J. Craik,

Bioconjugate Chemistry

2018

20

Multipurpose peptides: The venoms of Amazonian stinging ants contain anthelmintic ponericins with diverse predatory and defensive activities

Samantha A. Nixon, Samuel D. Robinson, Akello J. Agwa,

Biochemical Pharmacology

2021

20

Weaponisation ‘on the fly’: Convergent recruitment of knottin and defensin peptide scaffolds into the venom of predatory assassin flies

Jiayi Jin, Akello J. Agwa, Tibor G. Szántó,

Insect Biochemistry and Molecular Biology

2019

18

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