Deirdre Murphy Piedmonte

Sorbitol Crystallization Can Lead to Protein Aggregation in Frozen Protein Formulations

Deirdre Murphy Piedmonte, Christie Summers, Arnold McAuley et al. · Pharmaceutical Research · 2006 · 99 citations

Protein Chemistry, Biochemistry, Protein Aggregation +8

In Vivo Crystallization of Human IgG in the Endoplasmic Reticulum of Engineered Chinese Hamster Ovary (CHO) Cells

Haruki Hasegawa, John Wendling, Feng He et al. · Journal of Biological Chemistry · 2011 · 72 citations · Full text

A Case Study of Nondelamination Glass Dissolution Resulting in Visible Particles: Implications for Neutral pH Formulations

Gayathri Ratnaswamy, Alison Hair, Gary Li et al. · Journal of Pharmaceutical Sciences · 2014 · 20 citations

Materials Science, Glass-ceramic, Chemical Engineering +9

Beyond Glass Transitions: Studying the Highly Viscous and Elastic Behavior of Frozen Protein Formulations Using Low Temperature Rheology and Its Potential Implications on Protein Stability

Jian Gu, Alice Beekman, Tian Wu et al. · Pharmaceutical Research · 2012 · 16 citations

Rheological Measurement, Glass Transitions, Protein Folding +10

Sorbitol Crystallization-Induced Aggregation in Frozen mAb Formulations

Deirdre Murphy Piedmonte, Alison Hair, Priti Baker et al. · Journal of Pharmaceutical Sciences · 2014 · 15 citations · Full text

Frozen Mab Formulations, Self-assembly, Micro-encapsulation +2