James C. McGuire

The chemical structure of prostaglandin X (prostacyclin)

Roy A. Johnson, Douglas R. Morton, John H. Kinner et al. · Prostaglandins · 1976 · 730 citations

Medicinal Chemistry, Bioorganic Chemistry, Aldo-keto Reductase +7

Ia binding ligands and cAMP stimulate nuclear translocation of PKC in B lymphocytes

John C. Cambier, M. Karen Newell, Louis B. Justement et al. · Nature · 1987 · 315 citations

Signal Transduction, Cell Regulation, Cell Trafficking +6

Metabolism of prostaglandin endoperoxide in animal tissues

F.F. Sun, Justin Chapman, James C. McGuire · Prostaglandins · 1977 · 287 citations

Animal Physiology, Medicine, Lipid Peroxidation +9

Transmembrane signaling through B cell MHC class II molecules: anti-Ia antibodies induce protein kinase C translocation to the nuclear fraction.

Zehua Chen, James C. McGuire, Karen L. Leach et al. · The Journal of Immunology · 1987 · 98 citations

Anti-ia Antibodies, Adaptive Immune System, Immunology +23

Monoclonal antibodies specific for type 3 protein kinase C recognize distinct domains of protein kinase C and inhibit in vitro functional activity.

Karen L. Leach, Elaine A. Powers, James C. McGuire et al. · Journal of Biological Chemistry · 1988 · 80 citations · Full text

Immunocytochemical Technique, Signal Transduction, Protein Kinase C +12