Enhanced fatty acid oxidation provides glioblastoma cells metabolic plasticity to accommodate to its dynamic nutrient microenvironment

Shiva Kant, Pravin Kesarwani, Antony Prabhu, +4

Cell Death and Disease

Metabolic RemodelingGliomaTumor BiologyOxidative StressMetabolic Reprogramming +24

Tryptophan Metabolism Contributes to Radiation-Induced Immune Checkpoint Reactivation in Glioblastoma

Pravin Kesarwani, Antony Prabhu, Shiva Kant, +6

Clinical Cancer Research

USP2a Protein Deubiquitinates and Stabilizes the Circadian Protein CRY1 in Response to Inflammatory Signals

Xin Tong, Katie L. Buelow, Anirvan Guha, +2

Journal of Biological Chemistry

Usp2a Protein DeubiquitinatesMolecular RegulationMolecular BiologyCryptochromeCellular Physiology +18

Quinolinate promotes macrophage-induced immune tolerance in glioblastoma through the NMDAR/PPARγ signaling axis

Pravin Kesarwani, Shiva Kant, Yi Zhao, +4

Nature Communications

Low Dose Brain Irradiation Reduces Amyloid-β and Tau in 3xTg-AD Mice

George D. Wilson, Thomas G. Wilson, Alaa Hanna, +9

Journal of Alzheimer s Disease

EngineeringRadiation EffectRadiation ExposureRadiation BiologyRadiation Medicine +17

Recruitment of Histone Methyltransferase G9a Mediates Transcriptional Repression of Fgf21 Gene by E4BP4 Protein*

Xin Tong, Deqiang Zhang, Katie L. Buelow, +4

Journal of Biological Chemistry

Perhexiline Demonstrates FYN-mediated Antitumor Activity in Glioblastoma

Shiva Kant, Pravin Kesarwani, Anthony R. Guastella, +5

Molecular Cancer Therapeutics

Peroxisomal Localization and Circadian Regulation of Ubiquitin-Specific Protease 2

Matthew M. Molusky, Di Ma, Katie L. Buelow, +2

PLoS ONE

ProteasomePeroxisomal LocalizationMetabolic SyndromeMetabolic SignalingProteomics +19

Intratumoural haematopoietic stem and progenitor cell differentiation into M2 macrophages facilitates the regrowth of solid tumours after radiation therapy

Tyler M. Parsons, Katie L. Buelow, Alaa Hanna, +7

British Journal of Cancer

Amelioration of Mucositis in Proton Therapy of Fanconi Anemia Fanca^−/− Mice by JP4-039

Thomas J. Quinn, Xuanfeng Ding, Xiaoqiang Li, +11

In Vivo