The Metabolomic Signature of Malignant Glioma Reflects Accelerated Anabolic Metabolism

Prakash Chinnaiyan, Elizabeth Kensicki, Gregory Bloom, +7

Cancer Research

Cysteine Catabolism: A Novel Metabolic Pathway Contributing to Glioblastoma Growth

Antony Prabhu, Bhaswati Sarcar, Soumen Kahali, +5

Cancer Research

Chemoprevention StrategyMetabolomic ProfilingMetabolic RemodelingGliomaRedox Biology +18

Enhanced fatty acid oxidation provides glioblastoma cells metabolic plasticity to accommodate to its dynamic nutrient microenvironment

Shiva Kant, Pravin Kesarwani, Antony Prabhu, +4

Cell Death and Disease

Metabolic RemodelingGliomaTumor BiologyOxidative StressMetabolic Reprogramming +24

Targeting Radiation-Induced G2 Checkpoint Activation with the Wee-1 Inhibitor MK-1775 in Glioblastoma Cell Lines

Bhaswati Sarcar, Soumen Kahali, Antony Prabhu, +4

Molecular Cancer Therapeutics

Phase I trial of vorinostat combined with bevacizumab and CPT-11 in recurrent glioblastoma

Prakash Chinnaiyan, Sajeel Chowdhary, Lisa Potthast, +8

Neuro-Oncology

Chemoprevention StrategyPharmacotherapyHigh-grade GliomasMetronomic ChemotherapyRecurrent Glioblastoma +16

Tryptophan Metabolism Contributes to Radiation-Induced Immune Checkpoint Reactivation in Glioblastoma

Pravin Kesarwani, Antony Prabhu, Shiva Kant, +6

Clinical Cancer Research

Metabolic remodeling contributes towards an immune-suppressive phenotype in glioblastoma

Pravin Kesarwani, Antony Prabhu, Shiva Kant, +1

Cancer Immunology Immunotherapy

Neuro-oncologyGliomaMetabolic ReprogrammingMetabolic RemodelingTumor Suppressor +5

Quinolinate promotes macrophage-induced immune tolerance in glioblastoma through the NMDAR/PPARγ signaling axis

Pravin Kesarwani, Shiva Kant, Yi Zhao, +4

Nature Communications

Integrative cross-platform analyses identify enhanced heterotrophy as a metabolic hallmark in glioblastoma

Antony Prabhu, Shiva Kant, Pravin Kesarwani, +4

Neuro-Oncology

Class I histone deacetylases localize to the endoplasmic reticulum and modulate the unfolded protein response

Soumen Kahali, Bhaswati Sarcar, Antony Prabhu, +2

The FASEB Journal