R. E. PIKE

Discovery of Narlaprevir (SCH 900518): A Potent, Second Generation HCV NS3 Serine Protease Inhibitor

Ashok Arasappan, Frank Bennett, Stéphane Bogen et al. · ACS Medicinal Chemistry Letters · 2010 · 98 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Highly stereoselective access to novel 2,2,4-substituted tetrahydrofurans by halocyclization: Practical chemoenzymatic synthesis of Sch 51048, a broad-spectrum orally active antifungal agent

Anil K. Saksena, Viyyoor Girijavallabhan, Raymond G. Lovey et al. · Tetrahedron Letters · 1995 · 41 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9

Total synthesis and absolute stereochemistry of the antifungal dipeptide Sch 37137 and its 2S,3S - isomer

D. F. Rane, Viyyoor Girijavallabhan, Ashit K. Ganguly et al. · Tetrahedron Letters · 1993 · 34 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13

Enantioselective synthesis of the optical isomers of broad-spectrum orally active antifungal azoles, Sch 42538 and Sch 45012

Anil K. Saksena, Viyyoor Girijavallabhan, Raymond G. Lovey et al. · Bioorganic & Medicinal Chemistry Letters · 1994 · 28 citations

Pharmacy, Medicinal Chemistry, Pharmacology +9

Posaconazole (Noxafil, SCH 56592), a new azole antifungal drug, was a discovery based on the isolation and mass spectral characterization of a circulating metabolite of an earlier lead (SCH 51048)

Amin A. Nomeir, Birendra N. Pramanik, Larry Heimark et al. · Journal of Mass Spectrometry · 2007 · 21 citations

Medicine, Medicinal Chemistry, Pharmacology +15