Richard R. Gontarek

Discovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of Rapamycin

Steven D. Knight, Nicholas D. Adams, Joelle L. Burgess et al. · ACS Medicinal Chemistry Letters · 2010 · 367 citations · Full text

Highly Potent Inhibitor, Tumor Biology, Mammalian Target +16

Myelosuppression and kinase selectivity of multikinase angiogenesis inhibitors

Rakesh Kumar, M-C Crouthamel, David H. Rominger et al. · British Journal of Cancer · 2009 · 218 citations · Full text

Induced-fit tightens pleuromutilins binding to ribosomes and remote interactions enable their selectivity

Chen Davidovich, Anat Bashan, T. Auerbach-Nevo et al. · Proceedings of the National Academy of Sciences · 2007 · 194 citations · Full text

Remote Interactions, Protein Assembly, Biomolecular Structure Prediction +22

Distinct Concentration-Dependent Effects of the Polo-like Kinase 1–Specific Inhibitor GSK461364A, Including Differential Effect on Apoptosis

Aidan G. Gilmartin, Maureen R. Bleam, Mark C. Richter et al. · Cancer Research · 2009 · 131 citations · Full text

Effects of oncogenic p110α subunit mutations on the lipid kinase activity of phosphoinositide 3-kinase

Jeffrey D. Carson, Glenn Van Aller, Ruth Lehr et al. · Biochemical Journal · 2007 · 118 citations

Signal Transduction, Signaling Pathway, Biochemistry +12